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Editorial Board
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IFC
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| Hot Topic |
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Defective homologous recombination in human cancers
29 June 2011
Abstract: Homologous recombination (HR) is a process by which DNA double strand breaks are repaired through the alignment of homologous sequences of DNA. Interest continues to increase in HR pathway f...
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A. Cerbinskaite,
A. Mukhopadhyay,
E.R. Plummer,
N.J. Curtin,
R.J. Edmondson
et al.
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89-100
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| Controversy |
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Minimal residual disease in solid neoplasia: New frontier or red-herring?
26 May 2011
Abstract: Despite recent advances in prevention, screening, molecular characterization, and treatment, cancer evolution is still associated with late local, regional, or metastastic recurrence, even i...
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Pierre Mordant,
Yohann Loriot,
Benoît Lahon,
Yves Castier,
Guy Lesèche,
Jean-Charles Soria,
Christophe Massard,
Eric Deutsch
et al.
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101-110
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| Anti-Tumour Treatment |
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Is adjuvant radiotherapy needed after curative resection of extrahepatic biliary tract cancers? A systematic review with a meta-analysis of observational studies
08 June 2011
Summary: Background: The role for adjuvant radiotherapy (ART) after curative resection in extrahepatic cholangiocarcinoma remains unclear. Due to the lack of randomized trials, available data comes fr...
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Marta Bonet Beltrán,
Abdelkarim S. Allal,
Ignasi Gich,
Josep M. Solé,
Ignasi Carrió
et al.
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111-119
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Oral vinorelbine in metastatic breast cancer: A review of current clinical trial results
11 July 2011
Abstract: Background: Oral chemotherapy is one of the options for the treatment of endocrine non-responsive metastatic breast cancer. Patients and methods: A search of the online PubMed database was u...
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Matti Aapro,
Jindrich Finek
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120-126
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Multidisciplinary management of metastatic renal cell carcinoma in the era of targeted therapies
20 June 2011
Abstract: The use of targeted agents to treat metastatic renal cell carcinoma (mRCC) has significantly extended progression-free and overall survival but raises issues relating to the long-term delive...
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Bernard Escudier,
Susanne Osanto,
Börje Ljungberg,
Camillo Porta,
John Wagstaff,
Peter Mulders,
Martin Gore,
Axel Bex,
Joaquim Bellmunt,
Sergio Bracarda,
Alex Franklin,
Per Hartvig Honoré,
Alain Ravaud,
Jeanne van Steijn,
Zeba Aziz,
Hideyuki Akaza
et al.
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127-132
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| Laboratory-Clinic Interface |
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HER2 shedding and serum HER2 extracellular domain: Biology and clinical utility in breast cancer
09 May 2011
Abstract: The transmembrane protein HER2 is over-expressed in approximately 15% of invasive breast cancers as a result of HER2 gene amplification. HER2 proteolytic cleavage (HER2 shedding) generates s...
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Chantal Tsé,
Anne-Sophie Gauchez,
William Jacot,
Pierre-Jean Lamy
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133-142
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| New Drugs |
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Eribulin mesylate, a novel microtubule inhibitor in the treatment of breast cancer
10 May 2011
Summary: Background: Microtubule-targeted agents are one of the most common classes of chemotherapeutic drug for the treatment of breast cancer. Limitations of current microtubule-targeted agents such...
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Javier Cortes,
Alberto J. Montero,
Stefan Glück
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143-151
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| Complication of Treatment |
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The influence of chemotherapy on taste perception and food hedonics: A systematic review
26 May 2011
Summary: Purpose: Altered food relationships in people receiving chemotherapy are prevalent and distressing. Whether, or to what extent, taste perception and food hedonics plays in altered food relati...
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Anna Boltong,
Russell Keast
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152-163
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| General and Supportive Care |
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Radionuclide treatment of painful bone metastases in patients with breast cancer: A systematic review
17 June 2011
Abstract: Bone-seeking radionuclides, such as Sr-89, Sm-153, and Re-186, have been shown to have an effect on pain from bone metastasis in prostate cancer. The effect on bone pain in other cancer type...
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Mette H. Christensen,
Lars J. Petersen
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164-171
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