Ductal carcinoma in situ (DCIS) of the breast: evolving perspectives☆☆☆
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☆ 1This trial has since been published. See Firher B, Dignam J, Wolmark N et al. Tamoxifen in the treatment of intraductal breast cancer. National Surgical Adjuvant Breast and Bowel Project B-24 randomized controlled trial. Lancet 1999;353: 1993–2000.
☆☆ 2Some authors have proposed larger tumor size (> 4 cm) as an indication for mastectomy (3, 143). However, the larger the tumour, the more difficult to achieve complete tumour removal with satisfactory cosmetic result
PII: S0305-7372(99)90149-4
doi:10.1053/ctrv.1999.0149
