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Volume 38, Issue 1 , Pages 3-26 , February 2012

Cytostatic drugs in infants: A review on pharmacokinetic data in infants

Hendrik van den Berg
- Department of Pediatric Oncology, Emma Children Hospital – Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
- Medicines Evaluation Board, The Hague, The Netherlands
- Corresponding author. Address: Department of Paediatric Oncology, Emma Children Hospital Academic Medical Centre, University of Amsterdam, Room F8-242, P.O. Box 22700, 1100 DD Amsterdam, The Netherlands. Tel.: +31 20 5663050; fax: +31 20 6912231.
John N. van den Anker
- Division of Pediatric Clinical Pharmacology, Children’s National Medical Center, Washington, DC, USA
- Departments of Pediatrics, Pharmacology, and Physiology, George Washington University School of Medicine and Health Sciences, Washington, DC, USA
- Department of Pediatrics, Erasmus MC-Sophia Children’s Hospital, Rotterdam, The Netherlands
Jos H. Beijnen
- The Netherlands Cancer Institute, Slotervaart Hospital, Amsterdam, The Netherlands

Received 11 January 2011 ,Revised 21 March 2011 ,Accepted 24 March 2011.

Metabolism of cyclophosphamide. The enzymes with highest activity are depicted in bold.

Metabolism of cyclophosphamide. The enzymes with highest activity are depicted in bold.
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