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Cancer Treatment Reviews
Volume 37, Issue 2
, Pages 160-167
, April 2011
5-Azacytidine in myelodysplastic syndromes: A clinical practice guideline
References
- WHO classification of tumours: pathology and genetics of tumours of haematopoeitic and lymphoid tissues. Lyon: IARC Press; 2001;
- Proposals for the classification of the myelodysplastic syndromes. Brit J Haematol. 1982;51:189–199
- . Pathogenesis, etiology and epidemiology of myelodysplastic syndromes. Haematologica. 1998;83:71–86
- . Epidemiological and etiological aspects of myelodysplastic syndromes. Leukemia Lymphoma. 1995;16:247–262
- . Epidemiology, classification and prognosis of adults and children with myelodysplastic syndromes. Ann Hematol. 2008;87:691–699
- . Myelodysplastic syndromes. Hematology Am Soc Hematol Educ Program. 2004;297–317
- . Myelodysplastic syndromes: incidence and survival in the United States. Cancer. 2007;109:1536–1542
- . The myelodysplastic syndrome(s): a perspective and review highlighting current controversies. Leukemia Res. 2003;27:95–120
- Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study. Lancet Oncol. 2009;10:223–232
- Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B. J Clin Oncol. 2002;20:2429–2440
- Further analysis of trials with azacitidine in patients with myelodysplastic syndrome: studies 8421, 8921, and 9221 by the Cancer and Leukemia Group B. J Clin Oncol. 2006;24:3895–3903
- Impact of azacytidine on the quality of life of patients with myelodysplastic syndrome treated in a randomized phase III trial: a Cancer and Leukemia Group B study. J Clin Oncol. 2002;20:2441–2452
- Hematologic response to three alternative dosing schedules of azacitidine in patients with myelodysplastic syndromes. J Clin Oncol. 2009;27:1850–1856
- . Combination of 5-azacytidine and thalidomide for the treatment of myelodysplastic syndromes and acute myeloid leukemia. Cancer. 2008;113:1596–1604
- Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome. Blood. 2007;110:2302–2308
- Hydroxyurea, azacitidine and gemtuzumab ozogamicin therapy in patients with previously untreated non-M3 acute myeloid leukemia and high-risk myelodysplastic syndromes in the elderly: results from a pilot trial. Leukemia Lymphoma. 2008;49:2141–2147
- . Bioavailability of azacitidine subcutaneous versus intravenous in patients with the myelodysplastic syndromes. J Clin Pharmacol. 2005;45:597–602
- Effects of treatment with 5-azacytidine on the in vivo and in vitro hematopoiesis in patients with myelodysplastic syndromes. Leukemia. 1993;7(Suppl. 1):21–29
- List A, Fenaux G, Mufti J, et al. Effect on overall survival in higher-risk myelodysplastic syndromes (MDS) without complete remission. In: J Clin Oncol; 2008.
- Mufti G, Fenaux G, Hellstrom-Lindberg E, et al. Treatment of high-risk MDS patients (pts) with −7/del (7q) with azacitidine (AZA) versus conventional care regimens (CCR): effects on overall survival. In: J Clin Oncol: ASCO; 2008. p. 26 [abstract 7033].
- Seymour J, Fenaux P, Silverman L, et al. Effects of azacitidine (AZA) vs conventional care regimens (CCR) in elderly (⩾75 yrs) patients (Pts) with myelodysplastic syndromes (MDS) from the AZA-001 survival trial. In: ASH: Blood; 2008 [abstract 3629].
- Fenaux G, Mufti G, Hellstrom-Lindberg E, et al. Azacitidine prolongs overall survival (OS) and reduces infections and hospitalizations in patients (Pts) with WHO-defined acute myeloid leukemia (AML) compared with conventional care regimens (CCR). In: ASH, San Francisco: Blood; 2008 [abstract 3636].
- Silverman L, Fenaux G, Mufti G, et al. The effects of continued azacitidine (AZA) treatment cycles on response in higher-risk patients (Pts) with myelodysplastic syndromes (MDS). In: ASH, San Francisco: Blood; 2008 [abstract 227].
- Santini V, Fenaux G, Mufti G, et al. Management and supportive care measures of adverse events in higher risk MDS patients treated with azacitidine (AZA). In: Blood; 2008 [Abstract 1653].
- Report of an international working group to standardize response criteria for myelodysplastic syndromes. Blood. 2000;96:3671–3674
- Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia. Blood. 2006;108:419–425
- International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood. 1997;89:2079–2088
- . Standard and low-dose chemotherapy for the treatment of myelodysplastic syndromes. Leukemia Res. 1998;22(Suppl. 1):S17–S21
- . Low-dose ara-C in acute nonlymphocytic leukemia and myelodysplastic syndromes: a review of 20 years’ experience. Semin Oncol. 1987;14:126–133
- A predictive model for the clinical response to low dose ara-C: a study of 102 patients with myelodysplastic syndromes or acute leukaemia. Brit J Haematol. 1992;81:503–511
- Efficacy of intensive chemotherapy for acute myelogenous leukemia associated with a preleukemic syndrome. J Clin Oncol. 1989;7:1637–1645
- S-HAM induction chemotherapy with or without GM-CSF in patients with high-risk myelodysplastic syndromes. Ann Hematol. 1997;74:205–208
- Comparison of idarubicin
+
ara-C-, fludarabine
+
ara-C-, and topotecan
+
ara-C-based regimens in treatment of newly diagnosed acute myeloid leukemia, refractory anemia with excess blasts in transformation, or refractory anemia with excess blasts. Blood. 2001;98:3575–3583 - Intensive chemotherapy followed by allogeneic or autologous stem cell transplantation for patients with myelodysplastic syndromes (MDSs) and acute myeloid leukemia following MDS. Blood. 2001;98:2326–2331
- Results of intensive chemotherapy in 998 patients age 65 years or older with acute myeloid leukemia or high-risk myelodysplastic syndrome: predictive prognostic models for outcome. Cancer. 2006;106:1090–1098
- Intensive chemotherapy is not recommended for patients aged >60 years who have myelodysplastic syndromes or acute myeloid leukemia with high-risk karyotypes. Cancer. 2007;110:345–352
- Intensive chemotherapy with idarubicin, cytarabine, etoposide, and G-CSF priming in patients with advanced myelodysplastic syndrome and high-risk acute myeloid leukemia. Ann Hematol. 2004;83:498–503
- A decision analysis of allogeneic bone marrow transplantation for the myelodysplastic syndromes: delayed transplantation for low-risk myelodysplasia is associated with improved outcome. Blood. 2004;104:579–585
- . Allogeneic stem cell transplantation for myelodysplastic syndrome. Semin Hematol. 2008;45:49–59
- A comparison of low-dose cytarabine and hydroxyurea with or without all-trans retinoic acid for acute myeloid leukemia and high-risk myelodysplastic syndrome in patients not considered fit for intensive treatment. Cancer. 2007;109:1114–1124
- Brechignac S, Hellstrom-Lindberg E, Bowen DT, DeWitt TM, Cazzola M, Fenaux P. Quality of life and economic impact of red blood cell (RBC) transfusions on patients with myelodysplastic syndromes (MDS) In: ASH: Blood; 2004. p. 263b.
PII: S0305-7372(10)00105-2
doi: 10.1016/j.ctrv.2010.05.006
© 2010 Elsevier Ltd. All rights reserved.
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Cancer Treatment Reviews
Volume 37, Issue 2
, Pages 160-167
, April 2011
