Cancer Treatment Reviews
Volume 36, Issue 4 , Pages 348-353, June 2010

The contribution of the Epstein-Barr virus to the pathogenesis of childhood lymphomas

Cancer Research UK Institute for Cancer Studies, School of Cancer Sciences, University of Birmingham, Birmingham B15 2TT, UK

published online 02 March 2010.

Summary 

The Epstein-Barr virus (EBV) is a lymphotropic herpes virus with oncogenetic properties which can lead to the development of lymphomas such as Burkitt’s lymphoma (BL), Hodgkin’s lymphoma (HL), or post-transplant lymphoma. This review discusses our current understanding of lymphomagenesis in relation to EBV and the potential for targeted therapies.

Keywords: EBV, Lymphoma, Childhood, Herpes virus, Therapy

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PII: S0305-7372(10)00031-9

doi:10.1016/j.ctrv.2010.02.011

Cancer Treatment Reviews
Volume 36, Issue 4 , Pages 348-353, June 2010

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