Cancer Treatment Reviews
Volume 36, Issue 1 , Pages 83-90, February 2010

EORTC Elderly Task Force experts’ opinion for the treatment of colon cancer in older patients

  • A.G. Pallis

      Affiliations

    • EORTC Headquarters, EORTC-Elderly Task Force, Avenue E. Mounierlaan, 83/11, B-1200 Brussels, Belgium
    • Corresponding Author InformationCorresponding author. Tel.: +32 (0)2 774 10 62.
  • ,
  • D. Papamichael

      Affiliations

    • Dpt. of Medical Oncology, B.O.C. Oncology Center, Nicosia, Cyprus
  • ,
  • R. Audisio

      Affiliations

    • University of Liverpool, St. Helens Hospital, Marshalls Cross Road, St. Helens WA9 3DA, UK
  • ,
  • M. Peeters

      Affiliations

    • Dpt. of HepatoGastroenterology, Digestive Oncology Unit, University Hospital Gent, Ghent, Belgium
  • ,
  • G. Folprecht

      Affiliations

    • University Hospital Carl Gustav Carus, Medical Dept. I, Fetscherstr. 74, 01307 Dresden, Germany
  • ,
  • D. Lacombe

      Affiliations

    • EORTC Headquarters, EORTC-Elderly Task Force, Avenue E. Mounierlaan, 83/11, B-1200 Brussels, Belgium
  • ,
  • E. Van Cutsem

      Affiliations

    • Digestive Oncology Unit, University Hospital Gasthuisberg, 3000 Leuven, Belgium

Received 18 September 2009; received in revised form 28 October 2009; accepted 29 October 2009. published online 30 November 2009.

Summary 

As a result of an increasing life expectancy, the incidence of colon cancer in the older population is rising. As a consequence oncologists and their older patients commonly face the dilemma of whether or not to give/receive treatment for colon cancer. However, the paucity of large, well conducted prospective trials makes it difficult to provide evidence-based clinical recommendations for these patients. The current evidence supports the safety and efficacy of treatment for colon cancer in fit older patients and demonstrates that treatment outcome can be similar to that of their younger counterparts. However, it should be noted that these data are derived from retrospective studies which are likely to suffer from selection bias. Despite a growing body of data, further work is still needed to establish optimal strategies to care for this special population and prospective specific trials for older colon cancer patients are clearly needed.

Keywords: Colon cancer, Older, Age, Expert’s opinion, EORTC

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PII: S0305-7372(09)00161-3

doi:10.1016/j.ctrv.2009.10.008

Cancer Treatment Reviews
Volume 36, Issue 1 , Pages 83-90, February 2010