« Previous
Next »
Cancer Treatment Reviews
Volume 36, Issue 1
, Pages 24-32
, February 2010
Second-line treatment for malignant pleural mesothelioma
References
- . Advances in malignant mesothelioma. N Engl J Med. 2005;353:1591–1603
- . Multisciplinary treatment of malignant pleural mesothelioma. Oncologist. 2007;12:850–863
- Phase II study of pemetrexed with and without folic acid and vitamin B12 as front-line therapy in malignant pleural mesothelioma. J Clin Oncol. 2003;21:1556–1561
- Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma. J Clin Oncol. 2003;21:2636–2644
- Pemetrexed in malignant pleural mesothelioma. Clin Cancer Res. 2005;11:982–992
- Phase II study of pemetrexed plus carboplatin in malignant pleural mesothelioma. J Clin Oncol. 2006;24:1443–1448
- Phase II study of pemetrexed in combination with carboplatin in patients with malignant pleural mesothelioma (MPM). Ann Oncol. 2008;19:370–373
- Pemetrexed plus cisplatin or pemetrexed plus carboplatin for chemonaive patients with malignant pleural mesothelioma: results of the international expanded access program. J Thorac Oncol. 2008;3:756–763
- . Advances in the systemic therapy of malignant pleural mesothelioma. Nat Clin Pract Oncol. 2008;5:136–147
- . Chemotherapy of diffuse malignant mesothelioma. Phase II trials of single-agent 5-fluorouracil and adriamycin. Cancer. 1984;54:961–964
- Hoffman KR. Paclitaxel and carboplatin combination chemotherapy is an effective palliative treatment for malignant mesothelioma. Proc Am Soc Clin Oncol 1996;abstr. 1428.
- . Gemcitabine and cisplatin: second-line chemotherapy for malignant mesothelioma?. J Clin Oncol. 1999;17:2626–2627
- Karthaus M, Frieler F, Plahl A, Wert N, Tagizadeh K, Metzner D. Second line chemotherapy for patients with malignant mesothelioma (MPM) pretreated with pemetrexed and platinum. In: 2005 ASCO annual meeting proceedings, J Clin Oncol 2005;23(16S, Part I of II (June 1 Supplement)):7331.
- Phase II trial of ZD0473 as second-line therapy in mesothelioma. Eur J Cancer. 2002;38(Suppl. 8):19–24
- Raltitrexed-oxaliplatin combination chemotherapy is inactive as second-line treatment for malignant pleural mesothelioma patients. Lung Cancer. 2005;48:429–434
- Combination of raltitrexed and oxaliplatin is an active regimen in malignant mesothelioma: results of a phase II study. J Clin Oncol. 2003;21:349–354
- Efficacy and safety of first- or second-line irinotecan, cisplatin and mitomycin in mesothelioma. Cancer. 2007;109:93–99
- Prognostic factors in patients with pleural mesothelioma: the European Organization for Research and Treatment of Cancer experience. J Clin Oncol. 1998;16:145–152
- . Phase II study of vinorelbine in patients with malignant pleural mesothelioma. J Clin Oncol. 2000;18:3912–3917
- The efficacy and safety of weekly vinorelbine in relapsed malignant pleural mesothelioma. Lung Cancer. 2009;63:94–97
- . Pemetrexed as second-line treatment in malignant pleural mesothelioma after platinum-based first-line treatment. J Thorac Oncol. 2007;2:147–152
- Pemetrexed alone or in combination with cisplatin in previously treated malignant pleural mesothelioma: outcomes from a phase IIIB expanded access program. J Thorac Oncol. 2006;1:506–512
- Single-agent pemetrexed for chemonaïve and pretreated patients with malignant pleural mesothelioma: results of an international expanded access program. J Thorac Oncol. 2008;3:761–764
- Phase III trial of pemetrexed plus best supportive care compared with best supportive care in previously treated patients with advanced malignant pleural mesothelioma. J Clin Oncol. 2008;26:1698–1704
- Second-line (post-study) chemotherapy received by patients treated in the phase III trial of pemetrexed plus cisplatin versus cisplatin alone in malignant pleural mesothelioma. Ann Oncol. 2005;16:923–927
- . Retreatment with pemetrexed-based chemotherapy in malignant pleural mesothelioma (MPM): a second line treatment option. Lung Cancer. 2008;60:294–297
- Serke M, Bauer T. Pemetrexed in second-line therapy in patients with malignant pleural mesotelioma. In: 2007 ASCO annual meeting proceedings Part I, J Clin Oncol 2007;25(18S (June 20 Supplement):18198.
- De Vincenzo F, Zucali PA, Ceresoli GL, et al. Re-treatment with pemetrexed-based chemotherapy in patients with malignant pleural mesothelioma (MPM): an observational study. In: Proceedings of the IX international conference of the IMIG (International Mesothelioma Interest Group), Amsterdam (The Netherlands) 2008;abstr. 163.
- Xanthopoulos A, Bauer TT, Blum TG, Kollmeier J, Schonfeld N, Serke M. Gemcitabine combined with oxaliplatin in pretreated patients with malignant pleural mesothelioma: an observational study. J Occup Med Toxicol 2008;18:3(1):34 [Epub ahead of print].
- Gemcitabine and vinorelbine in pemetrexed-pretreated patients with malignant pleural mesothelioma. Cancer. 2008;112:1555–1561
- . Biology and management of malignant pleural mesothelioma. Eur J Cancer. 2006;42:2706–2714
- VEGF and VEGF type C play an important role in angiogenesis and lymphangiogenesis in human malignant mesothelioma tumours. Br J Cancer. 1999;81:54–61
- Vascular endothelial growth factor is an autocrine growth factor in human malignant mesothelioma. J Pathol. 2001;193:468–475
- Karrison T, Kindler HL, Gandara DR, et al. Final analysis of a multi-center, double-blind, placebo-controlled, randomized phase II trial of gemcitabine/cisplatin (GC) plus bevacizumab (B) or placebo (P) in patients (pts) with malignant mesothelioma (MM). In: 2007 ASCO annual meeting proceedings Part I, J Clin Oncol 2007:25(18S (June 20 Supplement)):7526.
- Ceresoli GL, Zucali PA, De Vincenzo F, et al. Phase II study of the combination of bevacizumab plus pemetrexed and carboplatin as first-line therapy in patients with malignant pleural mesothelioma (MPM). In: Proceedings of the IX international conference of the IMIG (International Mesothelioma Interest Group), Amsterdam (The Netherlands) 2008;abstr. 11.
- Kindler HL, Vogelzang NJ, Chien K, et al. SU5416 in malignant mesothelioma: a University of Chicago phase II consortium study. Proc Am Soc Clin Oncol 2001:20(abstr. 1359).
- . Thalidomide in patients with malignant pleural mesothelioma. Lung Cancer. 2005;48:291–296
- Pavlakis N, Abraham R, Harvie R, et al. Thalidomide alone or in combination with cisplatin/gemcitabine in malignant pleural mesothelioma (MM): interim results from two parallel non randomized phase II studies. Lung Cancer 2003;41(Suppl. 2):S11, abstr. O-26. Abstract of the 10th world conference on lung cancer.
- . Antiangiogenic therapies for mesothelioma. Hematol Oncol Clin N Am. 2005;19:1137–1145
- Janne PA, Wang XF, Krug LM, Hodgson L, Vokes EE, Kindler HL. Sorafenib in malignant pleural mesothelioma (MM): a phase II trial of the Cancer and Leukemia Group B (CALGB 30307). In: 2007 ASCO annual meeting proceedings Part I, J Clin Oncol 2007:25(18S (June 20 Supplement)):7707.
- Nowak A, Millward M, Francis R, et al. Phase II study of sunitinib as second-line therapy in malignant pleural mesothelioma (MPM). In: Proceedings of the IX international conference of the IMIG (International Mesothelioma Interest Group), Amsterdam (The Netherlands) 2008;abstr. 116.
- . Modified RECIST criteria for assessment of response in malignant pleural mesothelioma. Ann Oncol. 2004;15:257–260
- Early prediction of response to chemotherapy and survival in malignant pleural mesothelioma using a novel semiautomated 3-dimensional volume-based analysis of serial 18F-FDG PET scans. J Nucl Med. 2007;48:1449–1458
- Early response evaluation in malignant pleural mesothelioma by positron emission tomography with 18-F fluorodeoxyglucose. J Clin Oncol. 2006;24:4587–4593
- Phase II testing of sunitinib: the National Cancer Institute of Canada Clinical Trials Group IND Program Trials IND.182–185. Curr Oncol. 2007;14:154–161
- Garland LL, Chansky K, Wozniak A, et al. SWOG S0509: a phase II study of novel oral antiangiogenic agent AZD2171 (NSC-732208) in malignant pleural mesothelioma. J Clin Oncol 2009;27:15s (Suppl; abstr. 7511).
- Biological and clinical effects of intravenous tumor necrosis factor-alpha administered three times weekly. Cancer Res. 1991;51:1651–1658
- . Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13). Nat Biotechnol. 2000;18:1185–1190
- . Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration. J Clin Invest. 2002;110:475–482
- Zucali PA, Gregorc V, Ceresoli GL, et al. NGR-hTNF, a novel vascular targeting agent (VTA), as second-line therapy in malignant pleural mesothelioma (MPM): preliminary results of a multicenter phase II trial. In: Proceedings of the IX international conference of the IMIG (International Mesothelioma Interest Group), Amsterdam (The Netherlands) 2008;abstr. 10.
- Angiogenesis is an independent prognostic factor in malignant mesothelioma. Br J Cancer. 2001;85:863–868
- . Paraffin section detection of the c-kit gene product (CD 117) in human tissue: value in the diagnosis of mast cell disorders. Hum Pathol. 1998;29:498–504
- . Limited efficacy of imatinib mesylate in malignant mesothelioma: a phase II trial. Lung Cancer. 2005;50:83–86
- . Negative results of an Italian Group for Mesothelioma (G.I.Me.) pilot study of single-agent imatinib mesylate in malignant pleural mesothelioma. Cancer Chemother Pharmacol. 2007;59:149–150
- Millward M, Parnis F, Byrne M, et al. Phase II trial of imatinib mesylate in patients with advanced pleural mesothelioma. Proc Am Soc Clin Oncol 2003;22:228S (abstr. 912).
- Villano JL, Husain AN, Stadler WM, Hanson LL, Vogelzang NJ, Kindler HL. A phase II trial of imatinib mesylate in patients (pts) with malignant mesothelioma (MM). In: 2004 ASCO annual meeting proceedings (post-meeting edition), J Clin Oncol 2004:22(14S (July 15 Supplement)):7200.
- . EGFR expression: associations with outcome and clinicopathological variables in malignant pleural mesothelioma. Lung Cancer. 2006;54:399–407
- EGFR overexpression in malignant pleural mesothelioma. An immunohistochemical and molecular study with clinico-pathological correlations. Lung Cancer. 2006;51:207–215
- . Inhibition of epidermal growth factor signalling in malignant pleural mesothelioma. Cancer Res. 2002;62:5242–5247
- Erlotinib plus bevacizumab in previously treated patients with malignant pleural mesothelioma. Cancer. 2008;113:808–814
- Gefitinib in patients with malignant mesothelioma: a phase II study by the Cancer and Leukemia Group B. Clin Cancer Res. 2005;11:2300–2304
- Phase II study of erlotinib in patients with malignant pleural mesothelioma: a Southwest Oncology Group Study. J Clin Oncol. 2007;25:2406–2413
- . Common EGFR mutations conferring sensitivity to gefitinib in lung adenocarcinoma are not prevalent in human malignant mesothelioma. Int J Cancer. 2006;118:521–522
- . Histone deacetylase inhibitors: molecular mechanisms of action. Oncogene. 2007;26:5541–5552
- Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling. Oncogene. 2002;21:427–436
- Phase II study of belinostat (PXD101), a histone deacetylase inhibitor, for second line therapy of advanced malignant pleural mesothelioma. J Thorac Oncol. 2009;4:97–101
- . Ranpirnase and its potential for the treatment of unresectable malignant mesotelioma. Biologics. 2008;2:601–609
- Phase II trial of a single weekly intravenous dose of ranpirnase in patients with unresectable malignant mesothelioma. J Clin Oncol. 2002;20:274–281
- Reck M, Krzakowski M, Jassem J, et al. Randomized, multicenter phase III study of ranpirnase plus doxorubicin (DOX) versus DOX in patients with unresectable malignant mesothelioma (MM). J Clin Oncol 2009;27:15s (Suppl; abstr. 7507).
- . Emerging drugs for mesothelioma. Expert Opin Emerg. Drugs. 2007;12:127–137
- ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration. Cancer Res. 2002;62:4645–4655
- Novel dual targeting strategy with vandetanib induces tumor cell apoptosis and inhibits angiogenesis in malignant pleural mesothelioma cells expressing RET oncogenic rearrangement. Cancer Lett. 2008;265:55–66
- Betta PG, Castagneto B, Libener R, et al. The tyrosine kinase inhibitor ZD6474 inhibits cell proliferation and induces apoptosis in malignant mesothelioma. Ann Oncol 2006;17(Suppl. 9):ix57, abstr. 92PD.
- www.clinicaltrials.gov; A randomized Phase II trial to evaluate the efficacy and safety of Vandetanib (ZD6474, ZACTIMA™) versus vinorelbine in patients with inoperable or relapsed malignant mesothelioma; NCT00597116.
- . Everolimus. Nat Rev Drug Discov. 2009;8:535–536
- Phase I pharmacokinetic and pharmacodynamic study of the oral mammalian target of rapamycin inhibitor everolimus in patients with advanced solid tumors. J Clin Oncol. 2008;26:1588–1595
- www.clinicaltrials.gov; Phase II trial of mTOR inhibitor, Everolimus (RAD001), in malignant pleural mesothelioma (MPM); NCT00770120.
- Bortezomib inhibits nuclear factor-kB-dependent survival and has potent in vivo activity in mesothelioma. Clin Cancer Res. 2007;13:5942–5951
- Preclinical studies of the proteasome inhibitor bortezomib in malignant pleural mesothelioma. Cancer Chemother Pharmacol. 2008;61:549–558
- www.clinicaltrials.gov; An open label phase II multicentre clinical trial of single agent bortezomib in patients with malignant pleural mesothelioma; NCT00513877.
- Potential role of histone deacetylase inhibitors in mesothelioma: clinical experience with suberoylanilide hydroxamic acid. Clin Lung Cancer. 2006;7:257–261
- www.clinicaltrials.gov; A phase III, randomized, double-blin, placebo-controlled trial of oral suberoylanilide hydroxamic acid (SAHA) in patients with advanced malignant pleural mesothelioma previously treated with systemic chemotherapy; NCT00128102.
- Krug LM, Marangolo M, Kindler HL, et al. A phase III, randomized, double-blind, placebo-controlled trial of vorinostat in patients with (MPM) previously treated with systemic chemotherapy. In: Proceedings of the IX international conference of the IMIG (International Mesothelioma Interest Group), Amsterdam (The Netherlands) 2008;abstr. 223.
- Preliminary data suggestive of a novel translational approach to mesothelioma therapy: imatinib mesylate with gemcitabine or pemetrexed. Thorax. 2007;62:690–695
- Imatinib mesylate enhances therapeutic effects of gemcitabine in human malignant mesothelioma xenografts. Clin Cancer Res. 2008;14:541–548
- Phase I and pharmacokinetic study of imatinib mesylate (Gleevec) and gemcitabine in patients with refractory solid tumors. Clin Cancer Res. 2007;13:5876–5882
- www.clinicaltrials.gov; A Phase II study of the association of Glivec® plus Gemzar® in patients with unresectable, refractory, malignant mesothelioma; NCT00551252.
- Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion. Mol Cancer Ther. 2007;6:1962–1972
- www.clinicaltrials.gov; A phase II study of Dasatinib (NSC #732517) in patients with previously treated malignant mesothelioma; NCT00509041.
- . Mesothelin targeted cancer immunotherapy. Eur J Cancer. 2008;44:46–53
- . To cycle or not to cycle: a critical decision in cancer. Nat Rev Cancer. 2001;1:222–231
- . Cyclin-dependent kinase pathways as targets for cancer treatments. J Clin Oncol. 2006;24:1770–1783
- Global gene expression profiling of pleural mesotheliomas: overexpression of aurora kinases and P16/CDKN2A deletion as prognostic factors and critical evaluation of microarray-based prognostic prediction. Cancer Res. 2006;66:2970–2979
- Functional analysis of c-Met/Hepatocyte Growth Factor pathway in malignant pleural mesothelioma. Cancer Res. 2006;66:352–361
- . Insuline and insuline-like growth factors signalling in neoplasia. Nat Rev Cancer. 2008;8:915–928
- Effects of insuline-like growth factor-1 receptor inhibition in mesothelioma. Ann Thorac Surg. 2006;82:996–1002
PII: S0305-7372(09)00141-8
doi: 10.1016/j.ctrv.2009.09.003
© 2009 Elsevier Ltd. All rights reserved.
« Previous
Next »
Cancer Treatment Reviews
Volume 36, Issue 1
, Pages 24-32
, February 2010
