« Previous
Next »
Cancer Treatment Reviews
Volume 31, Issue 6
, Pages 448-455
, October 2005
The role of pentoxifylline as a modifier of radiation therapy
References
- Therapy of ischemic cardiomyopathy with the immunomodulating agent pentoxifylline: results of a randomized study. Circulation. 2004;109:750–755
- . Induction of acute phase gene expression by brain irradiation. Int J Radiat Oncol Biol Phys. 1995;33:619–626
- . The role of G2-block abrogation, DNA double-strand break repair and apoptosis in the radiosensitization of melanoma and squamous cell carcinoma cell lines by pentoxifylline. Int J Radiat Biol. 2000;76:1197–1208
- . Radiosensitization and DNA repair inhibition by pentoxifylline in NIH3T3 p53 transfectants. Int J Radiat Biol. 2002;78:991–1000
- . Effect of pentoxifylline on radiation-induced G2-phase delay and radiosensitivity of human colon and cervical cancer cells. Radiat Res. 1998;149:338–342
- . Preferential radiosensitization in p53-mutated human tumour cell lines by pentoxifylline-mediated disruption of the G2/M checkpoint control. Int J Radiat Biol. 2002;78:721–732
- Cell cycle perturbations and radiosensitization effects in a human prostate cancer cell line. J Cancer Res Clin Oncol. 2003;129:175–182
- The effects of pentoxifylline on the survival of human glioma cells with continuous and intermittent stereotactic radiosurgery irradiation. Int J Radiat Oncol Biol Phys. 2002;54:542–550
- . Physiological mechanisms of radiation sensitization by pentoxifylline. Anticancer Res. 2000;20:4605–4609
- . Pentoxifylline improves the oxygenation and radiation response of BA1112 rat rhabdomyosarcomas and EMT6 mouse mammary carcinomas. Int J Cancer. 2000;90:256–264
- . Pentoxifylline enhances tumor oxygenation and radiosensitivity in rat rhabdomyosarcomas during continuous hyperfractionated irradiation. Strahlenther Onkol. 2004;180:306–314
- . A study of hypoxic cell radiosensitizer applied to Ehrlich ascite tumour: a comparison of FC43 emulsion and pentoxyfilline. Br J Radiol. 2002;75:909–912
- . A phase II evaluation of pentoxifylline combined with radiation in the treatment of brain metastases. Int J Oncol. 1998;13:801–805
- . Cranial radiation and concomitant cisplatin and mitomycin-C plus resistance modulators for malignant gliomas. J Neurooncol. 1997;32:161–168
- Effect of pentoxifylline on radiation response of non-small cell lung cancer: a phase III randomized multicenter trial. Radiother Oncol. 2000;56:175–179
- Pentoxifylline does not spare acute radiation reactions in rat lung and skin. Radiat Res. 1992;129:107–111
- Effect of pentoxifylline on radiation-induced lung and skin toxicity in rats. Int J Radiat Oncol Biol Phys. 1995;31:71–77
- Modulation of radiation-induced tumour necrosis factor alpha (TNF-alpha) expression in the lung tissue by pentoxifylline. Radiother Oncol. 2002;64:177–187
- . Effect of high-dose pentoxifylline on acute radiation-induced lung toxicity in a rat lung perfusion model. Int J Radiat Oncol Biol Phys. 1996;34:111–115
- . Novel radioprotectant drugs for sparing radiation-induced damage to the physis. Int J Radiat Biol. 2004;80:217–228
- . Striking regression of subcutaneous fibrosis induced by high doses of gamma rays using a combination of pentoxifylline and alpha-tocopherol: an experimental study. Int J Radiat Oncol Biol Phys. 1999;43:839–847
- . Pentoxifylline in prevention of radiation-induced lung toxicity in patients with breast and lung cancer: a double-blind randomized trial. Int J Radiat Oncol Biol Phys. 2004;58:213–219
- . Prophylactic effect of pentoxifylline on radiotherapy complications: a clinical study. Otolaryngol Head Neck Surg. 2004;130:351–356
- . Preliminary results of a pilot study of pentoxifylline in the treatment of late radiation soft tissue necrosis. Int J Radiat Oncol Biol Phys. 1990;19:401–407
- . Pentoxifylline in the treatment of radiation-related soft tissue injury: preliminary observations. Laryngoscope. 1997;107:391–395
- . A pilot study of pentoxifylline in the treatment of radiation-induced trismus. Am J Clin Oncol. 2001;24:366–369
- Pentoxifylline in the treatment of radiation-induced fibrosis. J Clin Oncol. 2004;22:2207–2213
- . Pros and cons of antioxidant use during radiation therapy. Cancer Treat Rev. 2002;28:79–91
- . Uterine restoration by radiation sequelae regression with combined pentoxifylline-tocopherol: a phase II study. Fertil Steril. 2002;77:1219–1226
- . Randomized, placebo-controlled trial of combined pentoxifylline and tocopherol for regression of superficial radiation-induced fibrosis. J Clin Oncol. 2003;21:2545–2550
- Double-blind placebo-controlled randomised trial of vitamin E and pentoxifylline in patients with chronic arm lymphoedema and fibrosis after surgery and radiotherapy for breast cancer. Radiother Oncol. 2004;73:133–139
- . The radiation-induced fibroatrophic process: therapeutic perspective via the antioxidant pathway. Radiother Oncol. 2004;73:119–131
PII: S0305-7372(05)00127-1
doi: 10.1016/j.ctrv.2005.07.007
© 2005 Elsevier Ltd. All rights reserved.
« Previous
Next »
Cancer Treatment Reviews
Volume 31, Issue 6
, Pages 448-455
, October 2005
