Adjuvant chemotherapy with uracil–tegafur prolongs overall survival in people with primary adenocarcinoma of the lung: Abstracted from: Kato H, Ichinose Y, Ohta M, et al. A randomized trial of adjuvant chemotherapy with uracil–tegafur for adenocarcinoma of the lung. N Engl J Med 2004;350:1713–21.

References 

1. Non-Small Cell Lung Cancer Collaborative Group. Chemotherapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomized clinical trials. BMJ 1995;311:899–909
2. Ikenaka K, Shirasaka T, Kitano S, Fujii S. Effect of uracil on metabolism of 5-fluorouracil in vitro. Gann. 1979;70:353–359
   • MEDLINE
3. Shimizu E, Kimura K, Sone S, et al. A phase II study of UFT in non-small cell lung cancer. Gan To Kagaku Ryoho. 1986;13:2970–2973[in Japanese]
   • MEDLINE
4. Keicho N, Saijo N, Shinkai T, et al. Phase II study of UFT in patients with advanced non-small cell lung cancer. Jpn J Clin Oncol. 1986;16:143–146
   • MEDLINE
5. Wada H, Hitomi S, Teramatsu T. Adjuvant chemotherapy after complete resection in non-small cell lung cancer. J Clin Oncol. 1996;14:1048–1054
   • MEDLINE
6. Hamada C, Ohta M, Wada H, et al. Efficacy of oral UFT for adjuvant chemotherapy after complete resection of non-small cell lung cancer: meta-analysis of six randomized trials in 2003 patients. Prog Proc Eur Cancer Conf. 2003;39:S231;[abstract]
7. Shepherd FA, Pereira J, Ciuleanu TE, et al. A randomized placebo-controlled trial of erlotinib in patients with advanced non-small cell lung cancer (NSCLC) following failure of 1st line or 2nd line chemotherapy. A National Cancer Institute of Canada Clinical Trials Group (NCIC CTG) trial. Proc ASCO 2004, vol. 23 [abstract 7022]
8. Strauss GM, Herndon J, Maddaus MA, et al. Randomized clinical trial of adjuvant chemotherapy with paclitaxel and carboplatin following resection in Stage IB non-small cell lung cancer (NSCLC): Report of Cancer and Leukemia Group B (CALGB) Protocol 9633. Proc ASCO, vol 23 [abstract 7019]