« Previous
Next »
Cancer Treatment Reviews
Volume 30, Issue 7
, Pages 655-659
, November 2004
Gefitinib does not improve survival when combined with paclitaxel and carboplatin chemotherapy in people with advanced non-small-cell lung cancer: Abstracted from: Herbst RS, Giaccone G, Schiller JH et al. Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: a phase III trial – INTACT 2. J Clin Oncol 2004;22:785–94.
References
- . Cancer burden in the year 2000: The global picture. Eur J Cancer. 2001;37(Suppl 8):S4–S66
- . Chemotherapy in stage IV (metastatic) non-small-cell lung cancer. Cancer Prevention and Control. 1997;1:18–27
- Randomized phase III trial of paclitaxel plus carboplatin versus vinorelbine plus cisplatin in the treatment of patients with advanced NSCLC: A Southwest Oncology Group trial. J Clin Oncol. 2001;19:3210–3218
- Comparison of four chemotherapy regimens for advanced NSCLC. N Engl J Med. 2002;346:92–93
- . The epidermal growth factor receptor (EGFR): A new target in cancer therapy. Signal. 2000;1:4–11
- . The epidermal growth factor receptor and its inhibition in cancer therapy. Pharmacol Ther. 1999;82:241–250
- Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with NSCLC: a randomized trial. JAMA. 2003;290:2149–2158
- Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced NSCLC. J Clin Oncol. 2003;21:2237–2246
- Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor – selective tyrosine kinase inhibitor. Clin Cancer Res. 2000;6:2053–2063
- Efficacy of cytotoxic agents against human tumor xenograts is markedly enhanced by coadministration of ZD 1839 (Iressa), an inhibitor of EGFR tyrosine kinase. Clin Cancer Res. 2000;6:4885–4892
☆ Sources of funding: This study was funded by Astra Zeneca, Wilmington, Delaware, USA.
☆ For Correspondence: Roy Herbst, Department of Thoracic/Head and Neck Medical Oncology, University of Texas M.D. Anderson Cancer Center, Holcombe Blvd, Houston, TX, USA. E-mail: rherbst@mail.mdanderson.org
☆☆ Abstract provided by Bazian Ltd, London.
PII: S0305-7372(04)00144-6
doi: 10.1016/j.ctrv.2004.08.002
© 2004 Elsevier Ltd. All rights reserved.
« Previous
Next »
Cancer Treatment Reviews
Volume 30, Issue 7
, Pages 655-659
, November 2004
