« Previous
Next »
Cancer Treatment Reviews
Volume 30, Issue 5
, Pages 451-459
, August 2004
Molecular biology of sporadic gastric cancer: prognostic indicators and novel therapeutic approaches
References
- Cytogenetic findings in eleven gastric carcinomas. Cancer Genet. Cytogenet. 1993;68:42–48
- . Molecular biology of gastric cancer. Seminars in Radiation Oncology. 2002;12:128–140
- Clinical implications of chromosomal abnormalities in gastric adenocarcinomas. Genes Chromosomes Cancer. 2002;35:219–231
- Genetic differences between adenocarcinomas arising in Barrett's esophagus and gastric mucosa. Gastroenterology. 2001;121:592–598
- . Genetic alterations in Barrett's esophagus and adenocarcinomas of the esophagus and esophagogastric junction region. Am. J. Pathol. 1998;153:287–294
- Frequent loss of heterozygosity of the long arm of chromosome 7 is closely associated with progression of human gastric carcinomas. Int. J. Cancer. 1994;59:597–600
- . Evidence for two modes of allelic loss:multifocal analysis on both early and advanced gastric carcinomas. Virchows Arch. 2001;438:31–38
- . Microsatellite Instability occurs frequently in human gastric carcinoma. Oncogene. 1994;9:29–32
- Hypermethylation of the hMLH1 gene promoter in human gastric cancers with Microsatellite Instability. Cancer Research. 1999;59:1090–1095
- Distinct clinicopathologic and genetic profiles in sporadic gastric cancer with different mutator phenotypes. Genes Chromosomes Cancer. 2000;27:403–411
- Genetic progression in sporadic endometrial and gastrointestinal cancers with high microsatellite instability. J. Pathol. 2002;197:603–609
- . Histone Acetylation and Retinoic Acid Receptor beta DNA Methylation as Novel Targets for Gastric Cancer Therapy. Drug News Perspect. 2002;15:581–585
- . DNA methylation:an epigenetic pathway to cancer and a promising target for anticancer therapy. J. Oral. Pathol. Med. 2002;31:443–449
- . Epigenetic cancer therapies:DNA methyltransferase inhibitors. Expert Opin. Investig. Drugs. 2002;11:747–754
- . Reactivating the expression of methylation silenced genes in human cancer. Oncogene. 2002;21:5496–5503
- . DNA methyltransferase inhibitors-state of the art. Ann. Oncol. 2002;13:1699–1716
- . Epigenetic versus genetic alterations in the inactivation of E-cadherin. Semin. Cancer Biol. 2002;12:373–379
- E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma. Oncogene. 2001;20:1525–1528
- Association of CDH1 haplotypes with susceptibility to sporadic diffuse gastric cancer. Oncogene. 2002;21:8192–8195
- . Combined evaluation of mucin antigen and E-cadherin expression may help select patients with gastric cancer suitable for minimally invasive therapy. Br. J. Surg. 2003;90:95–101
- Expression of E-cadherin and β-catenin in gastric carcinoma and its correlation with the clinicopathological features and patient survival. World J. Gastroenterol. 2002;8:987–993
- Loss of E-cadherin expression in gastric intestinal metaplasia and later stage p53 altered expression in gastric carcinogenesis. Exp. Toxicol. Pathol. 2001;53:237–246
- . Apoptosis and cell proliferation in the development of gastric carcinomas:associations with c-myc and p53 protein expression. J. Gastroenterol. Hepatol. 2002;17:966–972
- . Combined evaluation of expressions of p53 and p21 proteins as prognostic factors for patients with gastric carcinoma. Oncology. 2002;63:353–361
- . Expression of p53, inducible nitric oxide synthase and vascular endothelial growth factor in gastric precancerous and cancerous lesions:correlation with clinical features. BMC Cancer. 2002;2(1):8
- . Clinical importance of serum anti-p53 antibodies as tumor markers. Rinsho Byori. 2002;50:970–975
- . Prognostic use of growth characteristics of early gastric cancer and expression patterns of apoptotic, cell proliferation, and cell adhesion proteins. J. Surg. Oncol. 2003;82:104–110
- . p53 and Ki-67 expression in epithelial gastric dysplasia and in gastric cancer. Panminerva Med. 2002;44:369–371
- . 5-Fluorouracil: mechanism of action and clinical strategies. Nature reviews cancer. 2003;3:330–338
- Biological markers as predictor of response and prognosis of unresectable gastric cancer patients treated with 5-fluorouracil and cis-platinum. Clin. Cancer Res. 1998;4:1469–1474
- Thymidilate synthase mRNA level in adenocarcinoma of the stomach:a predictor for primary tumour response and overall survival. J. Clin. Oncol. 1996;14:176–182
- thymidylate synthase protein expression. Cancer J. Sci. Am. 1995;1:49
- High expression of thymidilate synthase is associated with drug resistance of gastric adenocarcinoma to high dose 5-fluorouracil-based systemic chemotherapy. Cancer. 1998;82:1626–1631
- Immunohistochemical detection of thymidilate synthase in gastric cancer:a prognostic indicator in patients undergoing gastrectomy followed by adjuvant chemotherapy by 5-fluoropyrimidines. Anticancer Res. 1999;19:805–810
- Cyclooxygenase-2 expression during carcinogenesis in the human stomach. J. Pathol. 2002;196:171–179
- . Cyclooxygenase-2 expression is associated with well-differentiated and intestinal-type pathways in gastric carcinogenesis. Digestion. 2002;66:222–229
- . Expression of cyclooxygenase-2 and clinicopathologic features in human gastric adenocarcinoma. World J. Gastroenterol. 2003;9:250–253
- Inhibition of proliferation of gastric epithelial cells by a cyclooxygenase 2 inhibitor, JTE522, is also mediated by a PGE2-independent pathway. Aliment Pharmacol. Ther. 2002;16(Suppl 2):83–89
- Novel target for induction of apoptosis by cyclo-oxygenase-2 inhibitor SC-236 through a protein kinase C-beta (1)-dependent pathway. Oncogene. 2002;21:6113–6122
- The expression of proliferative-associated nuclear antigen p105 in gastric carcinoma. Cancer. 1991;67:2523–2528
- . The HER-2/neu Oncogene in tumors of the gastrointestinal tract. Cancer Investigation. 2001;19:554–568
-
Ougolkov A, Yamashita K, Bilim V, Takahashi Y, Mai M, Minamoto T. Abnormal expression of E-cadherin, beta-catenin, and c-erb B-2 in advanced gastric cancer:its association with liver metastasis. Int J Colorectal Dis 2003;18:160–6 [Epub 2002 Aug 10]
- Clinical significance of soluble c-erb B-2 levels in the serum and urine of patients with gastric cancer. Anticancer Res. 2002;22:3061–3065
- . Increased sensitivity to cisplatin in gastric cancer by antisense inhibition of the her-2/neu (c-erbB-2) gene. Chemotherapy. 2001;47:297–303
- . Impaired antibody-dependent cellular cytotoxicity mediated by herceptin in patients with gastric cancer. Cancer Res. 2002;62:5813–5817
- . The efficacy of ErbB receptor-targeted anticancer therapeutics is influenced by the availability of epidermal growth factor-related peptides. Cancer Res. 2002;62:3151–3158
- . Expression of vascular endothelial growth factor and its receptors KDR and Flt-1 in gastric cancer cells. World J. Gastroenterol. 2002;8:994–998
-
.
Vascular endothelial cell growth factor (VEGF), an emerging target for cancer chemotherapy.
Curr. Med. Chem. Anti-Canc. Agents. 2003;3:95–117
- . VEGF blocking therapy in the treatment of cancer. Expert Opin. Biol. Ther. 2003;3:263–276
- . Relationship between the expression of iNOS,VEGF,tumor angiogenesis and gastric cancer. World J. Gastroenterol. 2002;8:591–595
- Impact of epidermal growth factor (EGF) radioreceptor analysis on long-term survival of gastric cancer patients. Anticancer Res. 2002;22:1161–1167
- Clinical significance of the epidermal growth factor receptor and HER2 receptor in resectable gastric cancer. Ann. Surg. Oncol. 2003;10:234–241
-
Doi T, Koizumi W, Siena S, et al. Efficacy, tolerability and pharmacokinetics of gefinitib (ZD1839) in pretreated patients with metastatic gastric cancer. Proc ASCO 2003 [abstr 103]
-
Rojo F, Tabernero J, Van Cutsem E, et al. Pharmacodynamic studies of tumor biopsy specimens from patients with advanced gastric carcinoma undergoing treatment with gefinitib (ZD1839). Proc ASCO 2003 [abstr 764]
- . Relationship between recurrence and metastasis of gastric cancer and expression of EGFR, IL-6R, PCNA, and DI. Ai Zheng. 2002;21:785–789
- . Relationship of expression unbalance of matrix metalloproteinase and tissue inhibitor of metalloproteinase to invasiveness and metastasis in gastric carcinomas. Ai Zheng. 2002;21:305–310
- Marimastat as maintenance therapy for patients with advanced gastric cancer:a randomised trial. Br. J. Cancer. 2002;86:1864–1870
- Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer. N. Engl. J. Med. 2003;349:247–257
PII: S0305-7372(04)00027-1
doi: 10.1016/j.ctrv.2004.01.001
© 2004 Elsevier Ltd. All rights reserved.
« Previous
Next »
Cancer Treatment Reviews
Volume 30, Issue 5
, Pages 451-459
, August 2004
