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Cancer Treatment Reviews
Volume 29, Issue 5
, Pages 449-452
, October 2003
Sequential paclitaxel reduces recurrence and mortality in women with early breast cancer
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Paclitaxel (T) following doxorubicin/cyclophosphamide (AC) as adjuvant chemotherapy for node-positive breast cancer: results from NSABP B-28.
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Nabholtz J-M, Pienkowski T, Mackey J, Pawlicki M, Guastalla JP, Vogel C, Weaver C, Walley B, Martin M, Chap L, Tomiak E, Juhos E, Guevin R, Howell A, Hainsworth J, Fornander T, Blitz S, Gazel S, Loret C, Riva A., and Breast Cancer International Research Group. Phase III Trial Comparing TAC (Docetaxel, Doxorubicin, Cyclophosphamide) with FAC (5-Fluorouracil, Doxorubicin, Cyclophosphamide) in the Adjuvant Treatment of Node Positive Breast Cancer Patients: Interim Analysis of the BCIRG 001 Study. Proc Am Soc Clin Oncol 2002; 21
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Weekly (wkly) paclitaxel (P) followed by FAC as primary systemic chemotherapy (PSC) of operable breast cancer improves pathologic complete remission (pCR) rates when compared to every 3-week (Q 3 wk) P therapy (tx) followed by FAC – final results of a prospective phase III randomized trial.
Proc. Am. Soc. Clin. Oncol. 2002;21:35a
- Randomized trial of dose–dense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer: first report of Intergroup Trial C9741/Cancer and Leukemia Group B Trial 9741. J. Clin. Oncol. 2003;21:1431–1439
☆ Sources of funding: Supported in part by Grant no. CA31946 from the National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD. After completion of the trial, Bristol-Myers Squibb provided a grant for statistical and administrative support.
☆☆ For correspondence: I. Craig Henderson, MD, University of California at San Francisco, 1600 Divisadero St, Box 1710, San Francisco, CA 94143. E-mail: craig.henderson@accessoncology.com.
★ Abstract provided by Bazian Ltd., London.
PII: S0305-7372(03)00167-1
doi: 10.1016/S0305-7372(03)00167-1
© 2003 Elsevier Ltd. All rights reserved.
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Cancer Treatment Reviews
Volume 29, Issue 5
, Pages 449-452
, October 2003
