Uracil/tegafur plus oral leucovorin does not affect survival rates but may be better tolerated than standard fluorouracil and leucovorin for previously untreated metastatic colorectal cancer:☆☆☆★
Abstracted from: Douillard J, Hoff P, Skillings J et al. Multicenter phase III study of uracil/tegafur and oral leucovorin versus fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer. Journal of Clinical Oncology 2002; 20: 3605–16.
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☆ Sources of funding: Taiho Pharmaceutical Company, Japan; Bristol-Myers Squibb, New Jersey.
☆☆ For correspondence: Professor Douillard, Centre Rene Gauducheau, Site Hospitalier Nord, France. E-mail: jy-douillard@nantes.fnclcc.fr.
★ Abstract provided by Bazian Ltd, London.
PII: S0305-7372(02)00125-1
doi:10.1016/S0305-7372(02)00125-1
© 2003 Elsevier Science Ltd. All rights reserved.
