Cancer Treatment Reviews is an international review journal that will keep both the clinician and researcher abreast of modern concepts and developments in cancer treatment research through the publication of state of the art, authoritative reviews; evidence-based reviews (using a priori defined selection process to identify key articles from the literature and reviewing them in the form of a structured abstract, evidence summary and commentary); and systematic reviews. Cancer Treatment Reviews will increase publication frequency in 2004 to 8 issues per year.