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Evolving concepts in the management of drug resistant ovarian cancer: Dose dense chemotherapy and the reversal of clinical platinum resistance
18 May 2012
David J. Pinato, Janet Graham, Hani Gabra, Rohini Sharma
Abstract: Despite the initially high response rate to standard front-line debulking surgery followed by platinum-based chemotherapy, the relapse rate in ovarian cancer is high and many patients will r...
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Management of inflammatory breast cancer: Focus on radiotherapy with an evidence-based approach
07 May 2012
Vieri Scotti, Isacco Desideri, Icro Meattini, Vanessa Di Cataldo, Sara Cecchini, Alessia Petrucci, Ciro Franzese, Daniela Greto, Lorenzo Livi, Pierluigi Bonomo, Giampaolo Biti
Summary: Inflammatory breast cancer represents a rare and extremely aggressive subtype of breast cancer. Due to its rarity, prospective studies are a difficult goal to obtain in this field. Nowadays a...
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Hypoxia imaging using Positron Emission Tomography in non-small cell lung cancer: Implications for radiotherapy
07 May 2012
Vikram Rao Bollineni, Erwin M. Wiegman, Jan Pruim, Harry J.M. Groen, Johannes A. Langendijk
Abstract: Tumour hypoxia is an important contributor to radioresistance. Thus, increasing the radiation dose to hypoxic areas may result in improved locoregional tumour control. However, this strategy...
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Adjuvant trastuzumab in elderly with HER-2 positive breast cancer: A systematic review of randomized controlled trials
30 April 2012
Janaina Brollo, Giuseppe Curigliano, Davide Disalvatore, Bianca Fontana Marrone, Carmen Criscitiello, Vincenzo Bagnardi, Maximiliano Cassilha Kneubil, Luca Fumagalli, Marzia Locatelli, Silvia Manunta, Aron Goldhirsch
Abstract: Trastuzumab, in combination with chemotherapy, is the gold standard in the adjuvant treatment of patients with HER2 positive breast cancer. Limited data are available on the role of adjuvant...
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Swallowing dysfunction in head and neck cancer patients treated by radiotherapy: Review and recommendations of the supportive task group of the Italian Association of Radiation Oncology
30 April 2012
Elvio G. Russi, Renzo Corvò, Anna Merlotti, Daniela Alterio, Pierfrancesco Franco, Stefano Pergolizzi, Vitaliana De Sanctis, Maria Grazia Ruo Redda, Umberto Ricardi, Fabiola Paiar, Pierluigi Bonomo, Marco C. Merlano, Valeria Zurlo, Fausto Chiesa, Giuseppe Sanguineti, Jacques Bernier
Abstract: Purpose: Dysphagia is a debilitating complication in head and neck cancer patients (HNCPs) that may cause a high mortality rate for aspiration pneumonia. The aims of this paper were to summa...
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